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. 2017 Dec 19;9(3):4034–4043. doi: 10.18632/oncotarget.23428

Table 2. Univariate analysis of clinical characteristics associated with local progression-free survival (LPFS), relapse-free survival (RFS), and overall survival (OS).

LPFS RFS OS
Characteristics No. of patients, n 3 year (95% CI), % p-value 3 year (95% CI), % p-value 3 year (95% CI), % p-value
Gender Male 60 87.8 (78.1–97.5) 0.273 21.9 (6.6–37.2) 0.896 72.6 (59.7–85.5) 0.694
Female 11 100 (100) 36.4 (8.0–64.8) 81.8 (59.0–100)
Age, years <60 22 89.5 (79.2–99.8) 0.879 21.8 (4.1–39.5) 0.387 81.8 (65.7–97.9) 0.589
≥60 49 90.7 (78.4–100) 28.8 (13.4–44.2) 71.3 (60.0–85.6)
Aetiology of LC HBV 57 87.3 (77.2–97.4) 0.214 24.3 (11.6–37.0) 0.497 71.4 (58.2–84.7) 0.445
Others 14 100 (100) 38.7 (12.2–65.2) 85.7 (67.4–100)
Child–Pugh Classification A 68 89.6 (81.3–97.9) 0.665 27.5 (15.3–39.7) 0.051 76.4 (65.1–87.7) 0.034
B 3 100 (100) 0 (–) 33.3 (0–86.6)
AFP, ng/mL <10 43 88.8 (77.9–99.7) 0.882 33.7 (19.6–48.2) 0.098 84.2 (72.2–96.2) 0.032
≥10 28 92.1 (82.1–100) 17.0 (0–34.6) 60.0 (39.8–80.2)
Tumour size, cm <3 64 88.8 (80.0 -97.7) 0.426 24.6 (11.6–37.6) 0.413 74.6 (62.6–86.6) 0.697
≥3 7 100 (100) 42.9 (6.4–79.6) 71.4 (38.0–100)
AJCC stage I–II 66 89.3 (80.8–97.8) 0.534 25.9 (13.2–38.4) 0.658 77.8 (66.7–88.9) 0.030
IIIA 5 100 (100) 30.0 (0–76.8) 30.0 (0–76.8)
BCLC stage A 43 91.3 (81.5–100) 0.447 24.0 (8.8–39.3) 0.899 82.0 (69.6–94.4) 0.090
B 28 88.6 (76.4–100) 29.9 (10.9–48.8) 61.6 (40.3–82.9)
Pre-Tx to PBT site No 16 88.9 (68.4–100) 0.647 31.3 (8.6–54.0) 0.817 93.8 (81.9–100) 0.087
Yes 55 90.4 (82.4–98.4) 25.7 (11.7–39.6) 68.7 (91.9–82.5)
Pre-Tx to other site No 11 90.9 (73.9–100) 0.930 54.6 (25.2–84.0) 0.073 81.8 (59.0–100) 0.749
Yes 60 89.8 (80.9–98.7) 22.5 (10.5–34.5) 73.5 (61.2–85.8)
Tumour response CR 66 95.5 (89.1–100) <0.001 28.3 (15.8–40.9) 0.046 81.1% (70.6–91.5) <0.001
Non-CR 5 0 (–) 0 (–) 0 (–)

Abbreviations: CI, confidence interval; CR, complete response; all others are the same as in Table 1.

log-rank test.