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. 2017 Dec 23;9(3):4161–4172. doi: 10.18632/oncotarget.23647

Figure 1. Ophiopogonin B sensitizes TRAIL-initiated apoptosis in A549cells.

Figure 1

A549cells were pre-incubated with Ophiopogonin B at different doses (0, 2.5, 5, and 10 μM) for 12 h and exposed to TRAIL protein 200 ng/ml for 2 h. (A) Cell morphology photographed using light microscope (×100); (B) Cell viability was measured with crystal violet assay; (C) Bar graph indicating the average density of crystal violet; (D) Cell viability was assessed with trypan blue dye exclusion assays. **p < 0.01, ***p < 0.001: represent significant differences between control and each treatment group; OP-B: Ophiopogonin B; TRAIL: Tumor necrosis factor (TNF)-related apoptosis-inducing ligand.