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. 2017 Dec 23;9(3):4161–4172. doi: 10.18632/oncotarget.23647

Figure 8. Ophiopogonin B sensitizes TRAIL-initiated apoptosis in HCC-15 and Calu-3 cells.

Figure 8

HCC-15 and Calu-3 pre-incubated with varying concentrations of Ophiopogonin B (0, 2.5, 5, and 10 μM) for 12 h and exposed to TRAIL for 2 h. (A and D) Cell morphology photographed under light microscope (×100); (B and E) Cell viability determined with crystal violet assay; (C and F) Bar graph showing the average density of crystal violet dye; **p < 0.01, ***p < 0.001: represent significant differences between control and each treatment group; OP-B: Ophiopogonin B; TRAIL: Tumor necrosis factor (TNF)-related apoptosis-inducing ligand.