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. Author manuscript; available in PMC: 2018 Dec 1.
Published in final edited form as: Mayo Clin Proc. 2017 Oct 27;92(12):1772–1781. doi: 10.1016/j.mayocp.2017.09.011

Table 1.

Summary of previous studies that evaluated focal segmental glomerulosclerosis (FSGS) frequency or incidence

Study Time Period Location Type of FSGS Type of Study Findings
Haas, M., et al. (1995)1 1974–1993 Chicago, IL Excluded cases with clear risk factors for secondary glomerulonephritis Relative disease frequency FSGS relative frequency increased from 4% during 1974–1979 to 12.2% during 1987–1993
Korbet, S. M., et al. (1996)2 1975–1994 Chicago, IL Total FSGS Relative disease frequency FSGS accounted for 57% of glomerular lesions in blacks and 23% in whites. FSGS relative frequency increased from 39% in 1975–1984 to 64% in 1985–1994 among blacks.
Braden, G. L., et al. (2000)3 1974–1994 Springfield, MA Total FSGS Relative disease frequency Relative frequency of FSGS increased from 13.7% in 1975–1979 to 25% in 1990–1994. The increase was most notable in Blacks and Hispanics with only modest increase in Whites.
Swaminathan, S., et al. (2006)4 1974–2003 Olmsted County, MN Total FSGS Population-based Rate of FSGS increased from 0.1 per 100,000 person years in 1974–1983 to 1.8 per 100,000 person years in 1994–2003
Sim, J. J., et al. (2016)6 2000–2011 Southern California Total FSGS Population-based FSFS was the most common diagnosis (38.9%) across all race and ethnic groups. Incidence rate increased from 1.6 per 100,000 person years in 2000 to 5.3 per 100,0000 person years in 2011
Murugapandian, S., et al. (2016)5 2004–2014 Tuscon, AZ Total FSGS Relative disease frequency FSGS was the most common histopathological diagnosis (22%)
O'Shaughnessy, M. M., et al. (2017)7 1986–2015 Chapel Hill, NC Total FSGS Relative disease frequency Relative frequency of FSGS increased over three decades from 22.6% to 29.7%