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. Author manuscript; available in PMC: 2019 Jan 1.
Published in final edited form as: Hum Genet. 2017 Dec 20;137(1):85–94. doi: 10.1007/s00439-017-1858-8

Table 4.

Association between variant hsa-miR-4727-5p/rs73295187 and HDL under different modes of inheritance

Genetic model Discovery result Validation result

Beta P-value Beta P-value
Additive 4.312(0.9707) 9.45×10−6 1.224(0.9018) 0.1748
Recessive 13.47(4.572) 0.003265 13.25(3.655) 0.00030*
Dominant 4.198(1.035) 5.19×10−5 0.5029(0.9846) 0.6096
Genotypic - 2.07×10−5 - 0.00135*
*

The mode of inheritance showed significant association with HDL after Bonferroni correction.