A Volcano plot protein expressed in aggressive (n=4) vs. non-aggressive (n=4) MF. Fold-changes and p-value were plotted against each other. B. Cluster analysis of statistically significant proteins in patients with aggressive (n=4) and non-aggressive (n=4) MF. C. A representative sample of PARP-1 expression in the epidermotropic lymphocytes of patients with the early MF of the non-aggressive course, the the early MF of the aggressive course, and the advanced MF with the aggressive course. IHC, × 400. D. The mean IHC score of expression of PARP-1 on the epidermotropic lymphocytes in patients with the early MF of non-aggressive course (n=7), the early MF of the aggressive course (n=7), and the advanced MF with the aggressive course (n=5). **, p<0.01.