. 2018 Jan 11;11(1):35–44. doi: 10.14802/jmd.17046

Table 2.

Temporal parameters showing high sensitivity, specificity, area under curve and combination of loading and lifting phase duration, which segregated the maximum number of patients with PD from HCs at 1.7 N under the VWSC

Skin condition	Object weight	Parameter (s)	Cutoff	Sensitivity	Specificity	AUC	No. of PD patients screened (out of 25)	No. of controls screened (out of 50)
Parameters with high sensitivity, specificity and AUC
DSC	1.3 N	TPGF	0.38	0.92	0.90	0.94	22	45
		LPD	0.31	0.84	0.84	0.93	22	42
		LFD	0.64	0.80	0.80	0.89	20	40
VWSC	1.3 N	TPGF	0.34	0.84	0.84	0.95	20	43
		LPD	0.29	0.84	0.84	0.92	21	43
		LFD	0.64	0.80	0.80	0.86	20	41
DSC	1.7 N	TPGF	0.40	0.84	0.84	0.95	21	42
		LPD	0.31	0.84	0.84	0.93	21	42
		LFD	0.69	0.84	0.84	0.91	21	44
VWSC^*	1.7 N^*	TPGF	0.44	0.88^*	0.88^*	0.94^*	21	45
		LPD	0.36	0.84^*	0.84^*	0.91^*	20	43
		LFD	0.74	0.88^*	0.88^*	0.94^*	22	42
Combination of temporal parameters distinguished maximum number of PD patients from HCs at 1.7 N VWSC
VWSC^†	1.7 N^†	LPD	0.36	0.84	0.98	0.91	21	49
VWSC^†	1.7 N^†	LFD	0.74

object weight and skin condition which showed high sensitivity, specificity and area under curve,

^†

object weight and skin condition under which the maximum number of patients with PD can be distinguished from HCs by combining loading and lifting phase duration parameters.

DSC: dry skin condition, VWSC: very wet skin condition, TPGF: time to reach grip force, LPD: loading phase duration, LFD: lifting phase duration, N: Newtons, s: seconds, AUC: area under curve, PD: Parkinson’s disease, HCs: healthy controls.