Table 2.
Optimized compound dependent mass parameters for amiloride, hydrochlorothiazide and their labeled internal standards.
| Analytes and their labeled internal standards | Q1 mass (amu) | Q3 mass (amu) | Dwell time (ms) | Declustering potential (V) | Entrance potential (V) | Collision energy (eV) | Collision cell exit potential (V) |
|---|---|---|---|---|---|---|---|
| Amiloride | 230.6 | 116.0 | 300 | 55.0 | 10.00 | 43.0 | 11.0 |
| Amiloride-15N3 | 233.6 | 116.0 | 300 | 55.0 | 10.00 | 43.0 | 11.0 |
| Hydrochlorothiazide | 296.0 | 204.9 | 300 | −90.0 | −10.00 | −33.0 | −15.0 |
| Hydrochlorothiazide-13C,d2 | 299.0 | 205.9 | 300 | −90.0 | −10.00 | −33.0 | −15.0 |