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Matrix effect and extraction recovery of imatinib, dasatinib and nilotinib.
| Drug | Concentration (ng/mL) | Matrix effect (%) | RSD (%) | Extraction recovery (%) | RSD (%) |
|---|---|---|---|---|---|
| Imatinib | 5.3 | 110.0 | 9.1 | 62.5 | 7.2 |
| 525.0 | 112.4 | 6.6 | 53.2 | 10.0 | |
| 4725.0 | 113.8 | 1.7 | 67.9 | 4.8 | |
| Dasatinib | 4.9 | 110.9 | 4.6 | 64.2 | 13.0 |
| 147.0 | 108.8 | 6.0 | 63.7 | 12.8 | |
| 392.0 | 105.5 | 3.0 | 71.8 | 5.8 | |
| Nilotinib | 4.7 | 110.8 | 8.3 | 103.4 | 18.2 |
| 470.0 | 110.1 | 4.1 | 94.9 | 5.6 | |
| 4230.0 | 96.2 | 2.4 | 82.6 | 2.6 |
