Table 2.
Intra-day accuracy and precision data of the analytes.
| Qualitycontrol | Run | PIO |
TLM |
||||||
|---|---|---|---|---|---|---|---|---|---|
| Mean found (ng/mL) | SD | % CV | Accuracy % | Mean found (ng/mL) | SD | % CV | Accuracy % | ||
| LLOQ | 1 | 5.15 | 0.19 | 3.71 | 102.92 | 4.90 | 0.50 | 10.14 | 97.92 |
| 2 | 5.20 | 0.23 | 4.33 | 103.96 | 5.09 | 0.46 | 9.13 | 101.76 | |
| 3 | 5.27 | 0.17 | 3.19 | 105.44 | 4.86 | 0.40 | 8.21 | 97.24 | |
| 4 | 4.79 | 0.32 | 6.74 | 95.84 | 5.18 | 0.27 | 5.30 | 103.68 | |
| LQC | 1 | 15.24 | 0.93 | 6.11 | 101.60 | 14.46 | 0.83 | 5.72 | 96.40 |
| 2 | 14.32 | 1.00 | 7.01 | 95.47 | 14.46 | 1.07 | 7.39 | 96.40 | |
| 3 | 14.52 | 1.04 | 7.15 | 96.80 | 14.14 | 0.98 | 6.92 | 94.27 | |
| 4 | 14.72 | 0.53 | 3.58 | 98.13 | 14.86 | 0.57 | 3.82 | 99.07 | |
| MQC | 1 | 4404.00 | 168.02 | 3.82 | 97.87 | 4538.00 | 302.27 | 6.66 | 100.84 |
| 2 | 4644.00 | 254.13 | 5.47 | 103.20 | 4734.00 | 309.24 | 6.53 | 105.20 | |
| 3 | 4302.00 | 149.23 | 3.47 | 95.60 | 4616.00 | 275.92 | 5.98 | 102.58 | |
| 4 | 4388.00 | 199.67 | 4.55 | 97.51 | 4630.00 | 107.47 | 2.32 | 102.89 | |
| HQC | 1 | 8072.00 | 687.95 | 8.52 | 100.90 | 7650.00 | 491.07 | 6.42 | 95.63 |
| 2 | 7782.00 | 654.46 | 8.41 | 97.28 | 7918.00 | 442.12 | 5.58 | 98.98 | |
| 3 | 8488.00 | 422.46 | 4.98 | 106.10 | 8076.00 | 706.14 | 8.74 | 100.95 | |
| 4 | 7742.00 | 455.16 | 5.88 | 96.78 | 7868.00 | 463.86 | 5.90 | 98.35 | |
% CV: coefficient of variation. Accuracy: (Mean assayed concentration – nominal concentration)/(nominal concentration) × 100.