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. 2017 Dec 11;93(10):772–801. doi: 10.2183/pjab.93.049

Table 1.

Summary of results. The table summarizes the results of saccade studies performed by our group. Note that especially for cerebellar ataxia, which includes different neurological disorders, the findings are not necessarily consistent across studies reported to date.

Parameter Latency Amplitude Velocity Duration Impaired inhibitory control of saccades (frequency of saccades to cue)


Disorder VGS MGS VGS MGS
Focal lesion Parietal and posterior IC↑ Frontal-anterior IC↑Parietal and posterior IC↑ Parietal and posterior IC↓ Parietal and posterior IC↓ N for amplitude N for amplitude ↑ (Frontal, caudate and, parietal lesions)

PD (basal ganglia pattern) N at early stages ↑ At later stages N for amplitude N for amplitude

Cerebellar ataxia (cerebellar pattern) Slightly ↑ N Variable ↓ On average Variable → On average Slightly ↓ ↑ For cerebellarOutput lesions

PSP (brainstem pattern) ↓ At earliest stages ↑ At later stages ↓↓

PD: Parkinson’s disease, PSP: progressive supranuclear palsy, N: normal, Parietal and posterior IC: lesions of the parietal cortex and/or posterior limb of the internal capsule, Frontal-anterior IC: lesions of the frontal cortex and/or anterior limb of the internal capsule.