Table 1.
Parameter | Latency | Amplitude | Velocity | Duration | Impaired inhibitory control of saccades (frequency of saccades to cue) | ||
---|---|---|---|---|---|---|---|
Disorder | VGS | MGS | VGS | MGS | |||
Focal lesion | Parietal and posterior IC↑ | Frontal-anterior IC↑Parietal and posterior IC↑ | Parietal and posterior IC↓ | Parietal and posterior IC↓ | N for amplitude | N for amplitude | ↑ (Frontal, caudate and, parietal lesions) |
PD (basal ganglia pattern) | N at early stages ↑ At later stages | ↑ | ↓ | ↓ | N for amplitude | N for amplitude | ↑ |
Cerebellar ataxia (cerebellar pattern) | Slightly ↑ | N | Variable ↓ On average | Variable → On average | Slightly ↓ | ↑ For cerebellarOutput lesions | ↑ |
PSP (brainstem pattern) | ↓ At earliest stages ↑ At later stages | ↑ | ↓ | ↓ | ↓↓ | ↑ | ↑ |
PD: Parkinson’s disease, PSP: progressive supranuclear palsy, N: normal, Parietal and posterior IC: lesions of the parietal cortex and/or posterior limb of the internal capsule, Frontal-anterior IC: lesions of the frontal cortex and/or anterior limb of the internal capsule.