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. 2018 Jan 29;373(1742):20170036. doi: 10.1098/rstb.2017.0036

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© 2018 The Authors.

Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/4.0/, which permits unrestricted use, provided the original author and source are credited.

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Figure 3. — Summary of results for the modified ABT (mABT) showing reward-induced positive bias and its attenuation in putative models of depression. Animals exposed to early life adversity, chronic treatment with corticosterone, interferon alpha or retinoic acid all show impairments in their ability to learn the reward value and fail to bias their choices based on the higher value reward. In contrast to this anticipatory anhedonia, deficits in sucrose preference were only observed in animals receiving the chronic corticosterone treatment. ([75]; SA Stuart and ESJ Robinson 2015, unpublished). (Online version in colour.)