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. Author manuscript; available in PMC: 2018 Jan 31.
Published in final edited form as: Am J Physiol Heart Circ Physiol. 2002 Nov;283(5):H2140–H2150. doi: 10.1152/ajpheart.00462.2002

Table 1.

Statistical analysis of the exponential model compared with the sigmoidal model

β α
Lack of significant changes in exponential parameter values
ANOVA
 F statistic 0.77 1.51
 P value 0.5178 0.2290
PBonf = 0.0167
 PO vs. CL 0.4352 0.0536
 VO vs. CL 0.4850 0.3196
PHolm = 0.0250
 IS vs. Cl 0.0773 0.0418
A B C K1 K2
Significant changes in sigmoidal model parameter values
ANOVA
 F statistic 1.30 14.60 9.59 13.11 1.17
 P value 0.2889 0.0001 0.0001 0.0001 0.3404
PBonf = 0.0167
 PO vs. CL 0.4007 0.0001 0.0017 0.0065 0.0986
 VO vs. CL 0.1514 0.0001 0.0125 0.0007 0.4015
PHolm = 0.0250
 IS vs. CL 0.0895 0.0220 0.0161 0.0001 0.0380

PBonf = 0.0167 (i.e., 0.05/3), critical level for significance adjusted with the Bonferronian inequality; PHolm = 0.0250 (i.e., 0.05/2), critical level for significance adjusted according to the Holm modification; ANOVA, analysis of variance; CL, control; IS, ischemia; PO, pressure overload; VO, volume overload; α and β, exponential model parameters; A, B, C, K1, and K2, sigmoidal model parameters. Bold values denote significant change from CL.