Table 2.
Prediction of renal outcomes according to the presence of C3 deposits (0 versus ≥traces) or the Oxford classification (univariate Cox model)
| Outcome | Stage 3 CKD | ESRD | |||||
|---|---|---|---|---|---|---|---|
| n | HR | 95% CI | P Value | HR | 95% CI | P Value | |
| C3 deposits | 566 | 1.43 | 0.97 to 2.1 | 0.07 | 1.60 | 0.89 to 2.9 | 0.12 |
| M | 475 | 1.25 | 0.88 to 1.8 | 0.21 | 1.65 | 1.03 to 2.64 | 0.04 |
| E | 475 | 2.08 | 1.6 to 2.8 | <0.001 | 3.00 | 2.0 to 4.5 | <0.001 |
| S | 475 | 3.36 | 2.5 to 4.6 | <0.001 | 4.16 | 2.5 to 6.9 | <0.001 |
| T>0 | 475 | 8.60 | 6.4 to 11.6 | <0.001 | 11.5 | 7.6 to 17.5 | <0.001 |
| C>0 | 475 | 1.64 | 1.13 to 2.37 | <0.01 | 2.16 | 1.3 to 3.5 | 0.002 |
95% CI, 95% confidence interval; M, mesangial hypercellularity; E, endocapillary hypercellularity; S, segmental glomerulosclerosis; T, tubular atrophy/interstitial fibrosis; C, crescents.