Table 3.
Independent predictors of time to allograft loss at ABMR diagnosis: multivariable Cox model
Variable | Number of Patients | Number of Events | HR | 95% CI | P |
---|---|---|---|---|---|
eGFR (per 1-ml/min per 1.73 m2 increment) | 278 | 60 | 0.97 | (0.95 to 0.98) | <0.001 |
Chronic allograft glomerulopathy | |||||
Banff score=0 | 228 | 40 | 1 | ||
Banff score>0 | 50 | 20 | 2.25 | (1.29 to 3.92) | 0.004 |
Interstitial fibrosis/tubular atrophy | |||||
Banff score=0 | 130 | 16 | 1 | ||
Banff score>0 | 148 | 44 | 2.93 | (1.62 to 5.29) | <0.001 |
Anti-HLA DSA status | |||||
Preformed | 102 | 15 | 1 | ||
De novo | 176 | 45 | 2.45 | (1.34 to 4.47) | 0.004 |