Table 1.
Wild-type and CVVs used in this study.
| Virus | Abbreviation | Subtype | Virulence in ferrets | Reference | |
|---|---|---|---|---|---|
|
| |||||
| Wt lossa | Tempa | ||||
| A/swine/Missouri/2124514/2006 | sw/MO/06 | H2N3 | 13.7 | 1.7 | (Pappas et al., 2015) |
| A/swine/Missouri/2124514/2006 (H2N3)-PR8-IDCDC-RG27 | RG27 | H2N3 | 5.9 | 1.3 | This study |
| A/Egypt/N03072/2010 | Egypt/10 | H5N1 | 9.1 | 1.8 | (Pearce et al., 2016) |
| A/Egypt/N03072/2010(H5N1)-PR8-IDCDC-RG29 | RG29 | H5N1 | 1.2 | 1.0 | This study |
| A/duck/Vietnam/NCVD-1206/2012 | dk/VN/12 | H5N1 | 6.5 | 1.9 | (Pearce et al., 2016) |
| A/Hubei/1/2010(H5N1)-PR8-IDCDC-RG30 | RG30 | H5N1 | 3.8 | 0.8 | This study |
| A/Anhui/1/2013 | Anhui/13 | H7N9 | 11.0 | 1.5 | (Belser et al., 2013) |
| A/Shanghai/2/2013 (H7N9)-PR8-IDCDC-RG32A | RG32A | H7N9 | 1.5 | 1.5 | (Ridenour et al., 2015a) |
| A/gyrfalcon/Washington/41088-6/2014 | gyr/WA/14 | H5N8 | 3.5 | 1.3 | (Pulit-Penaloza et al., 2015) |
| A/gyrfalcon/Washington/41088-6/2014(H5N8)-PR8-IDCDC-RG43A | RG43A | H5N8 | 1.2 | 0.2 | This study |
| A/northern pintail/Washington/40964/14 | np/WA/14 | H5N2 | 0.5 | 1.4 | (Pulit-Penaloza et al., 2015) |
| IDCDC-RG47B (A/gyrfalcon/Washington/41088-6/2014 (H5N8)-PR8-IDCDC-RG43A-like HA, A/turkey/Minnesota/15-014110-1/2015 NA) × PR8 | RG47B | H5N2 | 0.3 | 1.2 | This study |
a
Mean maximum weight loss (expressed as percentage) and rise in pre-inoculation temperature (reported as °C above baseline) collected during the first 9 days p.i.