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. 2018 Jan 31;9:4. doi: 10.1186/s13227-017-0090-x

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Temporal dynamics of shh expression in the chick. a–c whole-mount views of embryos at HH stage 5 (a), 7 (b) and 8 (c); median sagittal technovit sections of stage 5 (d) and stage 7 (e); f–j transversal sections of HH stage 8 embryos at the levels shown in c. i median sagittal section of stage 8 embryo. Labeling: fp floor plate, am axial mesoderm, ec ectoderm, en endoderm, n node, pm prechordal mesoderm, sp preoral gut (prospective area of Seessel’s pouch), se superficial ectoderm, arrow—position of the node. Intersecting arrows indicate anatomical axes: A anterior, P posterior, L left, R right, D dorsal, V ventral. Scale bar 400 µm (a–c), 75 μm (e) and 50 µm (d, f–i)