Table 4.
Associations of serum lipid and apolipoprotein levels with rs1042034 genotype in HCV-positive and HCV-negative subjects
| HCV | Genotype of rs1042034 | P-value | |||
|---|---|---|---|---|---|
| AA (n) | GG + AG (n) | ||||
| TC | (mg/dl) | + | 160.9 ± 43.5 (11) | 170.3 ± 30.1 (138) | 0.342 |
| – | 205.7 ± 39.7 (6) | 207.1 ± 32.0 (194) | 0.917 | ||
| LDL-C | (mg/dl) | + | 86.2 ± 31.9 (11) | 97.7 ± 23.2 (114) | 0.134 |
| – | 121.5 ± 44.4 (6) | 124.9 ± 29.1 (202) | 0.779 | ||
| HDL-C | (mg/dl) | + | 47.1 ± 22.6 (9) | 53.6 ± 18.2 (110) | 0.313 |
| – | 56.5 ± 13.1 (6) | 63.1 ± 17.7 (192) | 0.370 | ||
| TG | (mg/dl) | + | 135.3 ± 66.1 (12) | 106.3 ± 54.8 (127) | 0.088 |
| – | 142.5 ± 31.5 (6) | 97.0 ± 55.4 (194) | 0.052 | ||
| APOA1 | (mg/dl) | + | 130.6 ± 35.8 (13) | 140.5 ± 31.1 (144) | 0.278 |
| – | 152.3 ± 27.0 (6) | 155.3 ± 29.3 (211) | 0.805 | ||
| APOA2 | (mg/dl) | + | 29.9 ± 5.6 (13) | 29.6 ± 5.5 (144) | 0.868 |
| – | 29.1 ± 3.5 (6) | 30.9 ± 4.9 (211) | 0.374 | ||
| APOB | (mg/dl) | + | 74.1 ± 21.8 (13) | 77.7 ± 17.6 (144) | 0.490 |
| – | 104.3 ± 35.3 (6) | 96.5 ± 22.4 (211) | 0.407 | ||
| APOC2 | (mg/dl) | + | 2.6 ± 1.3 (13) | 2.1 ± 1.0 (144) | 0.056 |
| – | 4.5 ± 2.6 (6) | 4.0 ± 1.6 (211) | 0.505 | ||
| APOC3 | (mg/dl) | + | 6.6 ± 2.7 (13) | 6.0 ± 2.3 (144) | 0.394 |
| – | 10.7 ± 3.9 (6) | 9.1 ± 3.0 (211) | 0.210 | ||
| APOE | (mg/dl) | + | 4.8 ± 2.0 (13) | 4.3 ± 1.0 (144) | 0.114 |
| – | 4.7 ± 1.7 (6) | 4.7 ± 1.2 (211) | 0.979 | ||
Values are presented as mean ± standard deviation. The number of subjects available for the analysis is shown in parentheses. P-values were calculated using Student‘s t-test