Table 3.
Characteristics of the macrophage-associated cytokines used in this study. The M1f characteristics were chosen to be similar to IL-6, while the M2f characteristics were chosen similar to IL-10
| Cytokine | Function | Source | MW (Da) | Diffusivity (as fraction of TAF diffusivity) |
|---|---|---|---|---|
| M1f | M1 differentiation | Proliferating & hypoxic tumor cells | 21,000 | 1 |
| M2f | M2 differentiation | Proliferating & hypoxic tumor cells | 18,606 | 3.7606 |
| IL-10 | TEM-eluted factor | TEM | 18,606 | 3.7606 |
| T2f | TEM differentiation | Proliferating & hypoxic tumor cells | 60,179 | 1 |
| Ang2 | TEM chemoattractant | Neovasculature | ~70,000 | 0.26591 |