Fig. 1.

Laquinimod prevents traumatic brain injury (TBI)-induced long-term lateral ventricle enlargement. a Representative × 10 images of brain sections, stained with cresyl violet, from sham and TBI mice (120 days following the brain injury) treated with laquinimod (LAQ) or vehicle (water). b A significant increase in lateral ventricle volume was found in TBI-water group, which was significantly prevented by laquinimod treatment. Symbols denote significant differences between groups. Error bars indicate mean ± s.e.m. (n = 3–4/group). *p < 0.05