Table 2.
Univariate and multivariate analyses showing potential risk factors for bacteremia in community-acquired pneumococcal pneumonia
| Variable | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
| OR (95% CI) | p-value | OR (95% CI) | p-value | |
| Age < 65 years | 3.00 (1.55–5.83) | 0.006a | 3.64 (1.73–7.67) | < 0.001a |
| Respiratory rate > 30 breaths·min−1 | 2.65 (1.39–5.03) | 0.003a | ||
| Heart rate > 125 beats·min−1 | 2.44 (1.12–5.35) | 0.03a | ||
| IRVS | 6.36 (2.90–13.9) | < 0.001a | 3.99 (1.71–9.33) | 0.001a |
| Serum albumin < 3.0 mg·dL−1 | 4.18 (2.21–7.92) | < 0.001a | 3.35 (1.63–6.87) | 0.001a |
| BUN >30 mg·dL−1 | 1.87 (0.97–3.57) | 0.06 | ||
| Serum sodium < 130 mEq·L−1 | 3.10 (1.05–9.13) | 0.04a | ||
| P/F ratio < 250 | 2.57 (1.36–4.85) | 0.004a | ||
| Serum CRP > 20 mg·dL−1 | 4.12 (2.18–7.77) | < 0.001a | 2.39 (1.21–4.75) | 0.01a |
adenotes significant value
Abbreviations: OR odds ratio, CI confidence interval, BUN blood urea nitrogen, P/F ratio PaO2/FiO2 ratio, CRP C-reactive protein, IRVS intensive respiratory or vasopressor support