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Safety parameters, according to the control arm (n=300) or active arm (n=202)
| Control arm (n=300), n (%) | Active arm (n=202), n (%) | P | |
|---|---|---|---|
| Drug-related side effects | 0 | 0 | - |
| Delirium | 11 (3.7) | 7 (3.5) | 0.91 |
| Median QTc presurgery | 423 (406-445) | 423 (404-444) | 0.24 |
| Median QTc postsurgery | 459 (440-484) | 456 (439-479) | 0.22 |
| QT prolongation* | 143 (47.7) | 110 (54.5) | 0.14 |
*QTc prolongation: QTc post- QTc presurgery above the median value (30 ms in our study)
