Figure 3.

Genomic analysis of the ERRLR01 gene region and the regulatory factors that interact with ERRLR01 using the UCSC Genome browser. Transcription orientation is depicted from right (5’ end) to left (3’ end). (A) ERRLR01.1 is a 4-exon gene conserved between mouse and human, and is expressed at high levels in testis, placenta, and brain tissue. (B, Top Panel) Detectable transcription is present across a panel of cell lines with evidence of H3K4Me1 modification. (B, Bottom Panel) Potential estrogen-regulated transcription factor binding locations are denoted, such as the GATA family of transcription factors, CTCF, and ERα itself.