Table 3.

HEPA vs. sham filtration comparison

	Outcome	% change*	Lower 95% CI	Upper 95% CI	Sample size
Full analysis	hsCRP	5.8%	−36.6%	76.5%	23
	IL-6	1.2%	−20.5%	29.0%
	TNFRII	3.3%	−3.0%	9.9%
Remove homes with least PNC reduction	hsCRP	15.6%	−43.6%	137.0%	18**
	IL-6	3.6%	−19.9	34.1%
	TNFRII	5.8%	−2.3%	14.6%
Remove homes with largest number of indoor spikes	hsCRP	−8.9%	−37.9%	33.7%	18**
	IL-6	0.3%	−25.8%	35.5%
	TNFRII	2.0%	−3.8%	8.3%

^*Adjusted for baseline; percent change is positive for higher blood biomarkers during HEPA.

^**The subgroup analyses are not the same set of participants, but instead the 18 participants with the largest PNC reduction and the fewest spikes respectively (see Table 2).