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(A) FDG-PET/CT scan acquisition. (B) Placement of a volume of interest on the primary tumor. (C) Tumor segmentation by isocontour with SUV of 3.5 (D) Gray scale resampling and texture feature extraction in global, local, and regional scales. Abbreviations: Co = Co-occurrence, NID = Neighborhood intensity difference, VA = Voxel alignment, ISZ = intensity size zone.
