Table 1. Parameters of interest in eligible studies.

P	Patients subjected to orthognatic surgery
I	Antibiotics on day of surgery i.e. short-termed prophylaxis Antibiotics more than day of surgery i.e.”extended” prophylaxis Head-to-head comparison of different antibiotic compounds or regiments
C	No antibiotic treatment Placebo Other non-antibiotic treatment e.g. such as antibacterial rinsing Other/comparing antibiotic treatment (alternative compound) Same compound, different dose/duration
O	Infection (primary) Quality of life (primary) Pain (primary) Mortality (primary) Osteosynthesis removal Sensory deficiency Patient reported out-come Relapse Length of hospital stay Length of sick leave Health economy Ethical aspects
Systematic reviews	Inclusion criteria Systematic review Systematic meta-analysis Exclusion criteria for systematic reviews
	Exclusion criteria Non-systematic review Guidelines Letter Position paper Consensus statements
Primary studies	Inclusion criteria English abstract Randomised control trials (RCT)
	Exclusion criteria Animal studies In vitro studies Any study type except RCT Lack of follow up