| Baqain ZH, Hyde N, Patrikidou A, Harris M. Antibiotic prophylaxis for orthognathic surgery: a prospective, randomised clinical trial. Br J Oral Maxillofac Surg. 2004;42(6):506–10. |
Unclear outcome measure |
| Bentley KC, Head TW, Aiello GA. Antibiotic prophylaxis in orthognathic surgery: a 1-day versus 5-day regimen. J Oral Maxillofac Surg. 1999;57(3):226–30; discussion 30–2. |
Unclear randomization process |
| Danda AK, Wahab A, Narayanan V, Siddareddi A. Single-dose versus single-day antibiotic prophylaxis for orthognathic surgery: a prospective, randomized, double-blind clinical study. J Oral Maxillofac Surg. 2010;68(2):344–6. |
Unclear randomization process, unclear report of methods |
| Davis CM, Gregoire CE, Davis I, Steeves TW. Prevalence of Surgical Site Infections Following Orthognathic Surgery: A Double-Blind, Randomized Controlled Trial on a 3-Day Versus 1-Day Postoperative Antibiotic Regimen. J Oral Maxillofac Surg. 2016:3. |
High drop-out |
| Eshghpour M, Khajavi A, Bagheri M, Banihashemi E. Value of prophylactic postoperative antibiotic therapy after bimaxillary orthognathic surgery: a clinical trial. Iranian journal of otorhinolaryngology. 2014;26(77):207–10. Epub 2014/10/17. |
Unclear randomization process and blinding |
| Fridrich KL, Partnoy BE, Zeitler DL. Prospective analysis of antibiotic prophylaxis for orthognathic surgery. Int J Adult Orthodon Orthognath Surg. 1994;9(2):129–31. |
Unclear randomization process and blinding |
| Jansisyanont P, Sessirisombat S, Sastravaha P, Bamroong P. Antibiotic prophylaxis for orthognathic surgery: a prospective, comparative, randomized study between amoxicillin-clavulanic acid and penicillin. J Med Assoc Thai. 2008;91(11):1726–31. |
Unclear randomization process and blinding |
| Kang SH, Yoo JH, Yi CK. The efficacy of postoperative prophylactic antibiotics in orthognathic surgery: a prospective study in Le Fort I osteotomy and bilateral intraoral vertical ramus osteotomy. Yonsei Med J. 2009;50(1):55–9. |
Unclear blinding and follow-up procedure |
| Ruggles JE, Hann JR. Antibiotic prophylaxis in intraoral orthognathic surgery. J Oral Maxillofac Surg. 1984;42(12):797–801. |
No baseline data reported, unclear follow-up procedure |
| Wahab PU, Narayanan V, Nathan S, Madhulaxmi. Antibiotic prophylaxis for bilateral sagittal split osteotomies: a randomized, double-blind clinical study. Int J Oral Maxillofac Surg. 2013;42(3):352–5. |
Unclear randomization process and blinding |
| Yoda T, Sakai E, Harada K, Mori M, Sakamoto I, Enomoto S. A randomized prospective study of oral versus intravenous antibiotic prophylaxis against postoperative infection after sagittal split ramus osteotomy of the mandible. Chemotherapy. 2000;46(6):438–44. |
Unclear randomization process |
| Zijderveld SA, Smeele LE, Kostense PJ, Bram Tuinztng D. Preoperative antibiotic prophylaxis in orthognathic surgery: A randomized, double-blind, and placebo-controlled clinical study. Journal of Oral and Maxillofacial Surgery. 1999;57(12):1403–6. |
Unclear randomization process and outcome measure |
