Table 4. Joint associations of pre- and post-physical activity and TV viewing with all-cause mortality among survivors of hematologic malignancies.
| TV viewing | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Physical activity | Pre-diagnosis | |||||||||||||
| All hematologic cancer survivors | NHL survivors | Myeloma survivors | Leukemia survivors | Acute leukemia survivors* | Chronic leukemia survivors | |||||||||
| High (≥3 to hrs/d) | Low (0 to 2 hrs/d) | High (≥3 to hrs/d) | Low (0 to 2 hrs/d) | High (≥3 to hrs/d) | Low (≥3 to hrs/d) | High (≥3 to hrs/d) | Low (0 to 2 hrs/d) | High (≥3 to hrs/d) | Low (0 to 2 hrs/d) | High (≥3 to hrs/d) | Low (0 to 2 hrs/d) | |||
| Low (<1 h/wk) | Deaths | 519 | 178 | 209 | 85 | 102 | 34 | 196 | 56 | 103 | 31 | 80 | 23 | |
| Multivariable-adjusted HR (95% CI) | 1.00 | 0.91 (0.77–1.08) | 1.00 | 0.91 (0.71–1.18) | 1.00 | 1.16 (0.78–1.74) | 1.00 | 0.89 (0.66–1.21) | 1.00 | 0.61 (0.41–0.93) | 1.00 | 0.98 (0.61–1.58) | ||
| High (≥1 h/wk) | Deaths | 1292 | 587 | 552 | 250 | 255 | 137 | 456 | 192 | 230 | 102 | 190 | 78 | |
| Multivariable-adjusted HR (95% CI) | 0.83 (0.75–0.92) | 0.74 (0.65–0.83) | 0.87 (0.74–1.02) | 0.71 (0.59–0.86) | 0.75 (0.59–0.95) | 0.93 (0.71–1.21) | 0.85 (0.71–1.01) | 0.70 (0.57–0.86) | 0.79 (0.61–1.01) | 0.64 (0.48–0.85) | 0.77 (0.58–1.004) | 0.66 (0.47–0.92) | ||
| Post-diagnosis | ||||||||||||||
| Low (<1 h/wk) | Deaths | 140 | 57 | 55 | 29 | 30 | 12 | 50 | 14 | 42 | 12 | |||
| Multivariable-adjusted HR (95% CI) | 1.00 | 0.83 (0.61–1.13) | 1.00 | 0.83 (0.53–1.31) | 1.00 | 0.76 (0.37–1.59) | 1.00 | 0.85 (0.46–1.60) | - | - | 1.00 | 0.89 (0.45–1.75) | ||
| High (≥1 h/wk) | Deaths | 234 | 142 | 115 | 70 | 39 | 29 | 74 | 40 | 61 | 30 | |||
| Multivariable-adjusted HR (95% CI) | 0.62 (0.5–0.77) | 0.63 (0.50–0.81) | 0.69 (0.50–0.95) | 0.62 (0.43–0.90) | 0.50 (0.29–0.85) | 0.67 (0.36–1.24) | 0.60 (0.41–0.88) | 0.57 (0.37–0.89) | - | - | 0.66 (0.43–1.01) | 0.62 (0.38–1.02) | ||
HR = hazard ratio, CI = confidence interval, TV = television, BMI = body mass index. Low PA = low physical activity (<1 hr/wk), High PA = high physical activity (≥1 hr/wk), Low TV = low television viewing (<3 hrs/d), High TV = high television viewing (≥3 hrs/d). Multivariable models are adjusted for age at exposure assessment (continuous), age at cancer diagnosis (continuous), education (less than 12 yrs, 12 yrs, vocational training or some college education, college graduate/postgraduate, unknown), race (non-Hispanic White, non-Hispanic Black, other, unknown), smoking (never smoker, former smoker with 20 cigarettes per day or less, former smoker with more than 20 cigarettes per day, current smoker with 20 cigarettes per day or less, current smoker with more than 20 cigarettes per day, missing), alcohol consumption (0, >0 to 14.9, ≥15g/d), hematologic cancer subtype (NHL, HL, myeloma, leukemia) and stage in NHL survivors (localized/regional/in situ, systemic disease, unknown/not abstracted/missing), and chemotherapy (yes, no, unknown/missing).
*Data were not evaluated for the post-diagnosis combination of physical activity and TV viewing due to low sample size.