Table 1. The most significant GO terms for T2D super enhancer SNPs target genes.
| GOID | Term | log_odds_ratio | p-value |
|---|---|---|---|
| GO:0048008 | platelet-derived growth factor receptor signaling pathway | 6.72 | 6.97E-13 |
| GO:0010172 | embryonic body morphogenesis | 7.70 | 7.26E-10 |
| GO:0050794 | regulation of cellular process | 1.14 | 4.98E-08 |
| GO:0023052 | Signaling | 1.64 | 1.10E-07 |
| GO:0044700 | single organism signaling | 1.64 | 1.10E-07 |
| GO:0050789 | regulation of biological process | 1.08 | 1.90E-07 |
| GO:0007154 | cell communication | 1.59 | 2.04E-07 |
| GO:0065007 | biological regulation | 1.02 | 3.75E-07 |
| GO:0007166 | cell surface receptor signaling pathway | 2.27 | 6.59E-07 |
| GO:0051974 | negative regulation of telomerase activity | 7.88 | 9.20E-07 |
| GO:0016055 | WNT signaling pathway | 3.99 | 3.00E-06 |
| GO:0198738 | cell-cell signaling by WNT | 3.99 | 3.00E-06 |
| GO:0007165 | signal transduction | 1.57 | 3.07E-06 |
| GO:0007186 | G-protein coupled receptor signaling pathway | 3.21 | 3.19E-06 |
| GO:0051972 | regulation of telomerase activity | 7.39 | 3.53E-06 |
GO enrichment analysis was performed using the GOEAST tool. The p-values were calculated by hypergeometric tests and adjusted for multiple comparisons using stringent Yekutieli (FDR under dependency) adjustment.