Table 2. Enriched gene ontologies of A673 (condition a)-specific hits.

	Term	# of genes	Enrichment	p-value
A	Hit list of more stringent ProFED profile: A ≤ -3 and B > 0 a
	GO:0006468 ~protein phosphorylation	8	22.7	7.30E-09
	GO:0035556 ~intracellular signal transduction	5	16	1.40E-04
	GO:0016572 ~histone phosphorylation	3	387.5	2.10E-05
B	Hit list of more open ProFED hit profile: A ≤ -3, B open, C ≤ -3 b
	GO:0006468 ~protein phosphorylation	14	18.4	5.20E-14
	GO:0035556 ~intracellular signal transduction	9	13.4	1.50E-07
	GO:0018105 ~peptidyl-serine phosphorylation	5	24	4.50E-05
	GO:0000082 ~G1/S transition of mitotic cell cycle	4	23.5	5.70E-04
	GO:0051301 ~cell division	4	6.9	1.80E-02
	GO:0016572 ~histone phosphorylation	3	179.9	1.10E-04
	GO:0061621 ~canonical glycolysis	3	69.2	7.90E-04
	GO:0018108 ~peptidyl-tyrosine phosphorylation	3	11.8	2.50E-02
	GO:0007049 ~cell cycle	3	8.3	4.70E-02

Biological process; p <0.05 and > 3 genes per category.

^a corresponding to Table 1A (13 hits).

^b corresponding to Table 1A plus 1B (28 hits).