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. 2018 Jan 31;13(1):e0191373. doi: 10.1371/journal.pone.0191373

Fig 5. Aged mice do not have a sex difference in food anticipatory activity.

Fig 5

(A) Mean (+/- SEM) seconds of high activity behaviors (hanging, jumping, rearing, and walking) on the first day of scheduled CR feeding in male (green) and female (blue) mice. (B) Normalized mean high activity of data shown in A. (C) Mean seconds of high activity behaviors after five weeks of timed CR feeding. (D)Normalized mean high activity of data shown in C. (E) Mean seconds of high activity data in the three hours preceding scheduled feeding across 42 days of the experiment. (F) Mean normalized high activity data in the three hours preceding scheduled feeding across 35 days of the experiment. (G) Mean body weights for aged males and female mice on a CR diet for five weeks. (H) Percentage weight loss calculated by normalizing to day 0. n = 3–6 for females and n = 6–8 for males * P<0.05, ***P<0.001, Mann-Whitney. The arrow indicated the time of expected food delivery (ZT7).