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. 2018 Jan 19;14(1):e1007185. doi: 10.1371/journal.pgen.1007185

Fig 1. Simultaneous removal of Toy/Tsh eliminates the eye-antennal disc.

Fig 1

(A) Schematic diagram of how the RD network regulates eye specification. (B) Schematic diagram of how the RD network might control cell proliferation. (C) Side view of a wild type head. (D) Dorsal view of a wild type head. (E) Light microscope image of a pair of eye-antennal discs (green arrows) from a wild type third instar larva. (F) Side view of a DE>toy RNAi + tsh RNAi pharate lethal headless adult. (G) Dorsal view of a DE>toy RNAi + tsh RNAi pharate lethal headless adult. (H) Light microscope image of the brain complex from a DE>toy RNAi + tsh RNAi third instar larva. The eye-antennal discs (red arrows) are rudimentary in size. (I) Side view of a DE>toy RNAi + tio RNAi adult head. (J) Side view of a DE>ey RNAi + tsh RNAi adult head. (K) Side view of a DE>ey RNAi + tio RNAi adult head. (Scale bars, 100 μm).