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(A) G-CSF, (B) IL-6, (C) CXCL1 and (D) CXCL2 levels were determined in the sera of WT or GKO mice at the indicated time points using a multiplex ELISA (n = 3–6 mice per time point). G-CSF: ****p<0.0001 for days 4, 6 and 8 pi; IL-6- all time points except day 6 pi and CXCL1: ****p<0.0001; CXCL2- all time points except day 6 pi: *p = 0.02.
