Table 4.

Correlations between changes in immune cell populations and changes in serum sex steroids, fat mass, and insulin sensitivity

	ΔSerum Total testosterone		ΔSerum 17β-Estradiol		ΔFat Mass		ΔMatsuda Index
	β-Coefficient	P value	β-Coefficient	P value	β-Coefficient	P value	β-Coefficient	P value
ΔCD3+, cells/g AT	−0.36	0.04	—	NS	−0.31	0.08	—	NS
ΔCD4+, cells/g AT	−0.34	0.04	—	NS	—	NS	—	NS
ΔCD8+, cells/g AT	−0.33	0.05	—	NS	−0.35	0.04	—	NS
ΔATMs, per g AT	—	NS	−0.34	0.05	—	NS	—	NS
ΔCD11c+, cells/g AT	−0.41	0.01	—	NS	—	NS	—	NS
ΔCD40+, cells/g AT	—	NS	—	NS	—	NS	0.42	0.01
ΔCD163+, cells/g AT	−0.36	0.03	—	NS	—	NS	—	NS
ΔDendritic, cells/g AT	—	NS	—	NS	—	NS	0.60	<0.0001

Correlations as determined by multistep linear regression between changes in immune cell numbers in AT and changes in serum levels of total testosterone and 17β-estradiol, fat mass, and insulin sensitivity as quantified by Matsuda index. Standardized β-coefficients are shown. Only statistically significant correlations or those evident as statistical trends were kept in the regression models.