Fig. 7.

Blockade of TRPV4 channels does not alter L-type Ca²⁺ channel-mediated [Ca²⁺]_i elevation and vasoconstriction in neonatal pig renal preglomerular arteries. Traces (A and C) and bar graphs (B and D) demonstrating that depolarization by 75 mM K⁺ stimulated renal artery wall [Ca²⁺]_i elevation (n = 5) and vasoconstriction (n = 7) that were abolished by nimodipine ([Ca²⁺]_i: n = 4; vasoconstriction: n = 5), but not HC 067047 ([Ca²⁺]_i: n = 4; vasoconstriction: n = 5). *P < 0.05 vs. 75 mM K⁺.