Figure 8.
The effect of ATP and UTP on VSMC survival and TNAP activity does not involve NPP1. The protective effects of (a) ATP and (b) UTP on cell viability were unchanged in Enpp1−/− VSMCs. The stimulatory actions of (c) ATP and (d) UTP on TNAP activity were the same in Enpp1+/+ and Enpp1−/− cells. Values are mean ± SEM (n = 6), *p < 0.05, ***p < 0.001