Table 3.

Changes in ln IRAK1 by ln IRAK1c and changes in ln MyD88_L by ln MyD88_S with corresponding 95% confidence intervals and P values

IRAK1 Model	Change in ln IRAK1 (95% CI)	P Value	MyD88-L Model	Change in ln MyD88-L (95% CI)	P Value
IRAK1c Healthy*	1.10 (1.02, 1.17)	<0.0001	MyD88-S Healthy	−0.21 (−0.59, 0.18)	0.294
IRAK1c ARDS*	1.10 (1.02, 1.17)	<0.0001	MyD88-S ARDS	0.25 (0.09, 0.42)	0.002
—	—	—	MyD88-S Difference	0.46 (0.04, 0.88)	0.032
Age, yr	0.00 (−0.01, 0.01)	0.752	Age, yr	0.00 (−0.01, 0.01)	0.929

^*Changes in IRAK1 by IRAK1c did not differ between healthy and acute respiratory distress syndrome (ARDS) subjects; the estimated change in ln IRAK1 for one unit change ln IRAK1c is the same regardless of affection status.