Fig. 3.

AQP1 increases the expression of β-catenin targets. A: bar graphs showing mean ± SE values for mRNA levels of the β-catenin targets, cyclin D1 and c-Myc, in PASMCs infected with viral constructs containing GFP (GFP; control), wild-type AQP1 (WT), or AQP1 with the COOH-terminal tail deleted (Mut); n = 11 for each group. B: representative immunoblot images show c-Myc and cyclin D1 protein levels. Bar graphs show means ± SE values for c-Myc and cyclin D1 protein normalized to β-tubulin. Data are expressed as fold change from GFP. *Significant difference from GFP value. n = 5–6 for each group.