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IL-13 deficiency is sufficient to attenuate the lung function decline. Bleomycin (100 µg id) was given to WT and IL-13 knockout mice for 4 wk to induce pulmonary fibrosis. At the end of 4 wk, resistance (A) and compliance (B) were measured using a FlexiVent. Data are presented as means ± SE (n = 5–6 mice/group), and unpaired Student’s t-test was used to measure the significant difference between the groups, *P < 0.05. All experiments were repeated 2 times with similar results.
