Table II.

Remodeling gene set used for the characterization of BAL cell profiling^∗

Gene name, alias†	Gene symbol†	Molecular functions
Chitinase 3-like 1	CHI3L1	Regulator of cell-matrix interactions
Collagen type VI α-2 chain	COL6A2	Matrix constituent
Fibronectin 1	FN1	Matrix constituent
Insulin-like growth factor 1	IGF1	Fibroblast proliferation and activation
Insulin-like growth factor binding protein 2	IGFBP2	Fibroblast proliferation and activation
Matrix metallopeptidase 7	MMP7	Mediator of matrix turnover; basement membrane proteolysis
Matrix metallopeptidase 9	MMP9	Mediator of matrix turnover; collagen and fibronectin proteolysis
Matrix metallopeptidase 12	MMP12	Mediator of matrix turnover; elastin proteolysis
Platelet-derived growth factor D	PDGFD	Fibroblast proliferation and survival
Secreted phosphoprotein 1, osteopontin	SPP1	Regulator of cell-matrix interactions
Thrombospondin 1	THBS1	Regulator of cell-matrix interactions; major activator of TGF-β1

^∗Primer and probe sequences are available in Table E1 in this article's Online Repository.

^†According to Human Gene Organization (HUGO) Gene Nomenclature Committee at the European Bioinformatics Institute.