Table 2.
Percent mammographic density (least square means and 95% confidence intervals) by alcohol consumption during different age intervals among premenopausal women.
Alcohol intake | No. of women | Model 1† | Model 2‡ |
---|---|---|---|
Ages 15–17, g/day | |||
0 | 942 | 40.9 (39.9, 41.9) | 41.6 (39.1, 44.1) |
>0 – <5 | 159 | 37.7 (35.5, 40.0) | 38.4 (35.4, 41.4) |
≥5 | 110 | 39.9 (37.1, 42.6) | 40.7 (37.1, 44.4) |
Ptrend =0.43 | Ptrend =0.50 | ||
Ages 18–22, g/day | |||
0 | 307 | 41.4 (39.7, 43.2) | 41.8 (38.8, 44.7) |
>0 – <5 | 385 | 40.4 (38.8, 42.0) | 41.1 (38.3, 43.8) |
≥5 – <10 | 394 | 39.5 (38.1, 40.9) | 40.1 (37.4, 42.7) |
≥10 | 125 | 40.6 (38.0, 43.3) | 41.0 (37.6, 44.4) |
Ptrend =0.61 | Ptrend =0.59 | ||
Ages 23–30, g/day | |||
0 | 280 | 39.9 (38.0, 41.7) | 40.4 (37.4, 43.5) |
>0 – <5 | 475 | 41.2 (39.9, 42.5) | 41.9 (39.3, 44.5) |
≥5 – <10 | 387 | 39.6 (38.1, 41.1) | 40.0 (37.4, 42.6) |
≥10 | 69 | 41.6 (37.9, 45.3) | 41.6 (37.1, 46.0) |
Ptrend =0.94 | Ptrend =0.75 | ||
Ages 31 – at mammogram, g/day | |||
0 | 260 | 39.6 (37.7, 41.4) | 40.0 (37.0, 43.0) |
>0 – <5 | 660 | 40.7 (39.6, 41.9) | 41.1 (38.5, 43.6) |
≥5 – <10 | 166 | 40.1 (37.7, 42.5) | 40.3 (37.2, 43.5) |
≥10 | 124 | 40.5 (37.9, 43.1) | 40.6 (37.1, 44.1) |
Ptrend =0.90 | Ptrend =0.92 |
adjusted for age (continuous) and BMI (continuous) at mammogram
further adjusted for parity, breast cancer in first-degree relative(s), benign breast disease, and use of oral contraceptives, all at or close to mammogram, as well as age at menarche, age at first pregnancy, and BMI at age 18