Table 3.
Percent mammographic density (least square means and 95% confidence intervals) by cumulative average consumption of alcohol prior to and after first full-term pregnancy† among premenopausal women.
Alcohol intake | No. of women | Model 1‡ | Model 2§ |
---|---|---|---|
Prior to first pregnancy, g/day | |||
0 | 187 | 41.6 (39.3, 44.0) | 41.5 (37.7, 45.2) |
>0 – <5 | 566 | 39.2 (37.9, 40.4) | 39.0 (36.0, 41.9) |
≥5 – <10 | 153 | 39.1 (36.7, 41.4) | 38.6 (35.2, 41.9) |
≥10 | 80 | 42.9 (39.5, 46.2) | 42.4 (38.2, 46.6) |
Ptrend =0.40 | Ptrend =0.50 | ||
After first pregnancy, g/day | |||
0 | 218 | 40.3 (38.2, 42.4) | 39.4 (35.8, 43.0) |
>0 – <5 | 548 | 39.3 (38.1, 40.5) | 38.9 (35.9, 41.8) |
≥5 – <10 | 142 | 41.5 (39.0, 44.1) | 40.9 (37.3, 44.6) |
≥10 | 65 | 40.6 (36.9, 44.3) | 39.4 (35.0, 43.8) |
Ptrend =0.36 | Ptrend =0.49 |
Full-term pregnancy was defined as a pregnancy lasting at least six months.
adjusted for age (continuous) and BMI (continuous) at mammogram
further adjusted for breast cancer in first-degree relative(s), benign breast disease, and use of oral contraceptives, all at or close to mammogram, as well as age at menarche, age at first pregnancy, and BMI at age 18