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. Author manuscript; available in PMC: 2019 Jan 1.
Published in final edited form as: Breast Cancer Res Treat. 2017 Sep 26;167(2):529–535. doi: 10.1007/s10549-017-4517-9

Table 3.

Percent mammographic density (least square means and 95% confidence intervals) by cumulative average consumption of alcohol prior to and after first full-term pregnancy among premenopausal women.

Alcohol intake No. of women Model 1 Model 2§
Prior to first pregnancy, g/day
 0 187 41.6 (39.3, 44.0) 41.5 (37.7, 45.2)
 >0 – <5 566 39.2 (37.9, 40.4) 39.0 (36.0, 41.9)
 ≥5 – <10 153 39.1 (36.7, 41.4) 38.6 (35.2, 41.9)
 ≥10 80 42.9 (39.5, 46.2) 42.4 (38.2, 46.6)
Ptrend =0.40 Ptrend =0.50
After first pregnancy, g/day
 0 218 40.3 (38.2, 42.4) 39.4 (35.8, 43.0)
 >0 – <5 548 39.3 (38.1, 40.5) 38.9 (35.9, 41.8)
 ≥5 – <10 142 41.5 (39.0, 44.1) 40.9 (37.3, 44.6)
 ≥10 65 40.6 (36.9, 44.3) 39.4 (35.0, 43.8)
Ptrend =0.36 Ptrend =0.49

Full-term pregnancy was defined as a pregnancy lasting at least six months.

adjusted for age (continuous) and BMI (continuous) at mammogram

§

further adjusted for breast cancer in first-degree relative(s), benign breast disease, and use of oral contraceptives, all at or close to mammogram, as well as age at menarche, age at first pregnancy, and BMI at age 18