Table III.
Features identified through three independent optimizations of 10-10-1 neural networks. Model 2 had the highest predictive accuracy on training (85.4%) and testing (84.3%) and was used to process all remaining sequences with unknown etiology as either brain or non-brain.
| Model 1 | Model 2 | Model 3 | |||
|---|---|---|---|---|---|
| Location | Feature | Location | Feature | Location | Feature |
| SH3 Binding | AA Comp SwissProt 2 | SH3 Binding | AA Comp Swiss Prot 2 | SH3 Binding | AA Comp Swiss Prot 2 |
| AP2 Binding | Grantham | AP2Binding | Grantham | ||
| Nef Loop | ChargeConversion | NefLoop | Charge Conversion | ||
| Nef Loop | Polarity 2 | Nef Loop | Polarity 2 | ||
| SH3 Binding | Parker | SH3 Binding | Parker | ||
| Cytokines Binding | Cowan | Cytokines Binding | Wilson | ||
| Cytokines Binding | Welling | Cytokines Binding | Welling | ||
| Alpha CD | Beta Sheet Levett | Alpha CD | Beta Sheet Levett | ||
| AP2 Binding | HPScale | AP2 Binding | HP Scale | ||
| Alpha CD | Transmembrane | Alpha CD | Transmembrane | ||
| AP2 Binding | Tanford | ||||
| Cytokines Binding | Aboderin | ||||
| AP2 Binding | Kyle Doolittle | ||||
| SH3 Binding | Antiparallel Beta | ||||
| AlphaCD | Janin | ||||
| Alpha Helix A | HP Scale | ||||
| AP2 Binding | Browne | ||||
| Alpha Helix A | Kyte Doolittle | ||||
| Nef Loop | Wolfenden | ||||