Table 1.
Characteristics of the sample at death (N=110)
| HIV+ N=84 |
HIV− N=26 |
|
|---|---|---|
| Mean age (in years, SD, median, interquartile range) | 50 (8.4, 50, 44–58) |
53 (11.8, 55, 55–81) |
| Male sex (%) | 71 | 58 |
| Ethnicity (%) | ||
| Non-Hispanic white | 20 | 39 |
| Non-Hispanic black | 50 | 27 |
| Hispanic | 30 | 34 |
| Hypertension (%) | 64 | 73 |
| Diabetes (%) | 19 | 46 |
| Dyslipidemia (%) | 23 | 19 |
| Smoking (%) | 60 | 35 |
| Hepatitis C co-infection (%) | 51 | 31 |
| cART use at death (%) | 69 | Not applicable |
| Prior opportunistic infections (%) | 80 | Not applicable |
| Mean Nadir CD4 (per mm3, SD, median, interquartile range) |
114 (71, 142, 11–172) |
Not applicable |
| Mean CD4 count at death (per mm3, SD, median, interquartile range) |
167 (82, 195, 15–268) |
Not applicable |
| CD4 count < 200% at death (%) | 67 | Not applicable |
| Viral load at death > 50 copies/ml (%) | 59 | Not applicable |
| Brain large artery unadjusted characteristics | ||
| Lumen diameter (in mm, mean ± SD) | 2.4 ± 0.8 | 2.2 ± 0.6 |
| Lumen to wall ratio | 6.9 ± 2.08 | 7.1 ± 2.0 |
| Wall thickness (in mm, mean ± SD) | 0.36 ± 0.11 | 0.32 ± 0.08 |
| Anterior frontal arteriolar unadjusted characteristics | ||
| Lumen diameter (in microns, mean ± SD) | 42.0 ± 0.33 | 31.5 ± 22.8 |
| Lumen to wall ratio | 3.36 ± 2.47 | 3.07 ± 2.13 |
| Wall thickness (in microns, mean ± SD) | 13.76 ± 8.59 | 11.00 ± 5.30 |
Abbreviations: N, number, SD, standard deviation; cART, combined antiretroviral therapy.