. Author manuscript; available in PMC: 2019 Feb 1.

Published in final edited form as: J Neurovirol. 2017 Dec 18;24(1):106–112. doi: 10.1007/s13365-017-0606-0

Table 2.

Relationship between large artery characteristics and downstream arterioles

		Arteriolar characteristics
		Lumen diameter (in microns) B estimate ± standard error	Wall thickness (in microns) B estimate ± standard error	Lumen-to-wall ratio B estimate ± standard error
Large artery characteristics
Lumen-to-wall ratio	All large arteries	0.31 ± 0.40	−0.12 ± 0.10	0.04 ± 0.03
Lumen-to-wall ratio	Ipsilateral to the arterioles	0.58 ± 0.29^†	−0.02 ± 0.04	0.05 ± 0.03^*
Lumen diameter (in mm)	All large arteries	1.46 ± 3.88	−1.14 ± 1.16	0.33 ± 0.37
Lumen diameter (in mm)	Ipsilateral to the arterioles	1.82 ± 0.77^†	0.08 ± 0.11	0.14 ± 0.07^†
Wall thickness (in mm)	All large arteries	−2.92 ± 7.76	2.27 ± 2.31	−0.66 ± 0.74
Wall thickness (in mm)	Ipsilateral to the arterioles	8.06 ± 3.65^†	−0.84 ± 0.77	−0.56 ± 0.36
Atherosclerosis (i.e. presence of atheroma)	All large arteries	0.31 ± 3.41	1.29 ± 1.09	−0.19 ± 0.29
Atherosclerosis (i.e. presence of atheroma)	Ipsilateral to the arterioles	−0.09 ± 3.59	0.82 ± 1.12	−0.10 ± 0.33

P value < 0.10–0.05

^†

P value <0.05

Analytic note: All models were adjusted for age, sex, race/ethnicity, hypertension, diabetes, dyslipidemia, smoking, hepatitis C, HIV, cocaine use, interadventitial size, large artery type and large artery proximal versus distal location.