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. Author manuscript; available in PMC: 2019 Feb 1.
Published in final edited form as: J Neurovirol. 2017 Dec 18;24(1):106–112. doi: 10.1007/s13365-017-0606-0

Table 3.

Models stratified by HIV status

Arteriolar characteristics
Lumen diameter (in microns) B estimate ± standard error Lumen-to-wall ratio B estimate ± standard error
Model 1 Model 2 Model 1 Model 2
Ipsilateral large artery characteristics HIV − HIV + HIV + HIV− HIV + HIV +
Lumen-to-wall ratio 0.05 ± 0.20 0.69 ± 0.35 0.37 ± 0.18 0.01 ± 0.02 0.06 ± 0.03* 0.04 ± 0.01
Lumen diameter (in mm) 0.39 ± 0.65 2.03 ± 0.89 1.56 ± 0.51 0.10 ± 0.07 0.14 ± 0.09 0.14 ± 0.04
Wall thickness (in mm) 3.63 ± 4.51 8.54 ± 4.17 9.15 ± 3.52 0.92 ± 0.49* 0.50 ± 0.40 0.75 ± 0.32
*

P value < 0.10–0.05

P value <0.05

P value < 0.01

Analytic note:

Model 1 adjusted for age, sex, race/ethnicity, hypertension, diabetes, dyslipidemia, smoking, hepatitis C, cocaine use, inter-adventitial size, large artery type and large artery proximal versus distal location. Model 2 includes model 1 plus prior opportunistic infections, use and class of antiretrovirals, nadir CD4 and CD4 counts prior to death, and viral loads > 50 copies per ml prior to death.