Table 3.
Arteriolar characteristics | ||||||
---|---|---|---|---|---|---|
Lumen diameter (in microns) B estimate ± standard error | Lumen-to-wall ratio B estimate ± standard error | |||||
Model 1 | Model 2 | Model 1 | Model 2 | |||
Ipsilateral large artery characteristics | HIV − | HIV + | HIV + | HIV− | HIV + | HIV + |
Lumen-to-wall ratio | 0.05 ± 0.20 | 0.69 ± 0.35† | 0.37 ± 0.18† | 0.01 ± 0.02 | 0.06 ± 0.03* | 0.04 ± 0.01‡ |
Lumen diameter (in mm) | 0.39 ± 0.65 | 2.03 ± 0.89 | 1.56 ± 0.51‡ | 0.10 ± 0.07 | 0.14 ± 0.09 | 0.14 ± 0.04‡ |
Wall thickness (in mm) | 3.63 ± 4.51 | 8.54 ± 4.17† | 9.15 ± 3.52† | 0.92 ± 0.49* | 0.50 ± 0.40 | 0.75 ± 0.32† |
P value < 0.10–0.05
P value <0.05
P value < 0.01
Analytic note:
Model 1 adjusted for age, sex, race/ethnicity, hypertension, diabetes, dyslipidemia, smoking, hepatitis C, cocaine use, inter-adventitial size, large artery type and large artery proximal versus distal location. Model 2 includes model 1 plus prior opportunistic infections, use and class of antiretrovirals, nadir CD4 and CD4 counts prior to death, and viral loads > 50 copies per ml prior to death.