Fig. 1. Polycystin-2 (PC2), β1-adrenoreceptor (β1AR), β2-adrenoreceptor (β2AR), SERCA2a and ryanodine receptor (RYR) protein expression after prolonged β-adrenergic stress.
Western blot analysis of PC2 (A), β1AR (B), β2AR (C), SERCA2a (D) and RyR (E) to alpha-tubulin expression in cardiac ventricular tissue of 6 week old male WT and Pkd2+/− mice after 7 days of control or isoproterenol (ISO: 25mg/kg/day) treatment and representative images of the blots. Each lane represents a different animal. Results are presented as the mean±sem. *, ** and **** mean p<0.05, 0.01 or 0.001, respectively. Two-way ANOVA, Tukey post test.