Fig. 5. Increased cardiac mass persists in Pkd2+/-, but not WT, mice after termination of chronic β-adrenergic stress.
Echocardiographic analysis of 6 week old male WT (white bar) and Pkd2+/− (black bar) mice after 7 days of isoproterenol (ISO; 25 mg/kg/day) or vehicle treatment and three days rest. (A) Left ventricular mass; (B) Heart weight to body weight ratio. Results are presented as the mean±sem. * and ** means p<0.05 or 0.01, respectively. Two-way ANOVA, Tukey post test.