Table 2.

Increased AD-related histopathology is associated with decrease in F-actin expression levels (see Fig. 7G–I)

Predictor variable1	p-value	Nature of association
Braak staging	5.60E-05	Negative
Square root amyloid load	0.011846	Negative
Square root tangle density	0.00062438	Negative

Control predictor variables were PMI and age at death. The dependent variable was F-actin. Ordinary least-squares regression-based GLM analysis (without considering variable interactions) demonstrates the effects of different AD-related histopathological scores such as Braak staging, total amyloid load, and total tangle density on the expression of F-actin when controlled for postmortem interval (PMI) and age at death.

n = 36 (n = 12 from each group).